Prenatal cytogenetic screening

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Prenatal screening of cytogenetic anomalies – a Western Indian experience

BACKGROUND Children born with congenital anomalies present a very high rate of perinatal death and neonatal mortality. Cytogenetic analysis is a convincing investigation along with clinical suspicion and biochemical screening tests. The current study was designed to characterize the prevalence and types of chromosomal abnormalities in high risk prenatal samples using different cytogenetic techn...

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Results and pitfalls in prenatal cytogenetic diagnosis.

Since 1969, we have cultured over 200 diagnostic amniotic fluids. Of these, 183 were for cytogenetic diagnosis. The chromosome analysis was successful in 168 cases. The indications and the results ofthe affected fetuses (followed by therapeutic abortion) are: (1) previous child with Down's syndrome: 62 cases (1 :47,XX,+21); (2) advanced maternal age: 54 cases (1 :47,XXY; 1 :45,X/46,XY mosaicism...

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Prenatal screening and genetics.

Although the term 'genetic screening' has been used for decades, this paper discusses how, in its most precise meaning, genetic screening has not yet been widely introduced. 'Prenatal screening' is often confused with 'genetic screening'. As we show, these terms have different meanings, and we examine definitions of the relevant concepts in order to illustrate this point. The concepts are i) pr...

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Prenatal Screening and Diagnosis

In recent years the prevalence of Down syndrome has been increasing. The increase in the prevalence might be partly explained by better compilation of statistics on Down syndrome today. Also, the mean maternal age at first delivery as well as the proportion of older moth‐ ers is increasing in all western countries and the risk of Down syndrome increases with ad‐ vancing maternal age [1]. The pr...

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Pnm-19: How Are Prenatal Screening Results after ART Success?

Background Down syndrome screening at first-trimester may cause a higher false positive rate in pregnant patients who have undergone assisted reproductive technologies (ART). Combining the second largest series of biophysical and biochemical tests in the first trimester of pregnancy after ART is mentioned in few studies. MaterialsAndMethods Ghisoni et al explored that NT measurement between ART...

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics and Gynecology

سال: 1995

ISSN: 0960-7692

DOI: 10.1046/j.1469-0705.1995.05010003.x